T cells have been found to play a pivotal role in the immune response against cancer. In fact, the adoptive transfer of T cells expressing genetically engineered chimeric antigen receptors (CARs)¹ has shown great promise in clinical studies addressing chronic or acute lymphocytic leukemia²-³. However, the preparation of CAR T cells for clinical application is quite complex and comprises numerous handling steps.
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- Maus, M. V. et al. (2014) Blood 123: 2625–2635.