クリニカルエリア - 免疫療法 - NK細胞

NK細胞

  • Versatile – Customized strategies for manufacturing of NK cell products
  • Convenient – CliniMACS® System in combination with MACS® GMP Products
  • Promising – Anti-tumor and -infection responses reported in numerous publications

Natural killer (NK) cells are major players of the innate immune system. They play a central role in immune surveillance and early immune responses to cancer and infection. NK cells might be explored as a tool for treatment of malignant disease in both transplant and non-transplant settings.

The use of specific CliniMACS® Product Lines allows GMP-compliant manufacturing of NK cell products according to the needs given by a specific treatment concept.

Highly enriched NK cell products are generated by CD3 depletion followed by CD56 enrichment. A combined NK cell and natural killer T (NKT) cell product is produced by a single CD56 enrichment step. Heterogeneous NK cell products can be manufactured by either CD3 or TCRα/β depletion, optionally in combination with CD19 depletion if B cell depletion is required. The latter two manufacturing strategies for NK cells allow co-enrichment of NK cells and accessory cells, such as monocytes and dendritic cells (DCs). In case of TCRα/β depletion, γ/δ T cells are also preserved within the NK cell product, and, potentially, this could have a clinical add-on value.

Find Products in CliniMACS マイクロビーズ
17 products available


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Product Order no. Price

CliniMACS Anti-Biotin MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-019-201 price on request here

CliniMACS CD1c (BDCA-1)-Biotin for Research Use

Regulatory status: For research use only, not for use in humans
Availability: worldwide (2)
Content: 5 mL

Availability

(2)日本国内での取扱の有無については、お問い合わせください
 
130-025-501 price on request here

CliniMACS CD3 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-017-601 price on request here

CliniMACS CD4 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-030-401 price on request here

CliniMACS CD8 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-030-801 price on request here

CliniMACS CD14 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-019-101 price on request here

CliniMACS CD19 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-019-301 price on request here

CliniMACS CD25 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-032-501 price on request here

CliniMACS CD45RA MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-020-003 price on request here

CliniMACS CD56 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)日本国内での取扱の有無については、お問い合わせください
 
130-019-401 price on request here
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Showing 1-10 of 17


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Contact

Miltenyi Biotec K.K.
TEL +81 3 5646 8910
FAX+81 3 5646 8911
macs@miltenyibiotec.jp
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